Chemotherapy Drug List

Antimicrobial Agents

Cell Wall Synthesis Inhibitors:

Penicillins
Narrow spectrum Penase-sensitive
     •   Pen G                            •   PEN V

Narrow spectrum Penase-resistent (S. aureus)
     •    NAFCILLIN                    •    OXACILLIN                    •    dicloxacillin

Broad spectrum (aminopenicillins)
     •    AMOXICILLIN                •    AMPICILLIN

Primarily antipseudomonal
     •    TICARCILLIN                 •    CARBENICILLIN

Extended spectrum
     •    PIPERACILLIN

Monobactams
     •   Aztreonam

Carbapenems
     •    Imipenem with cilastatin

Penicillin plus penicillinase inhibitor
     •    Amoxicillin plus            •    Ticarcillin plus
           clavulanic acid                   clavulanic acid
           (Augmentin)                      (Timentin)

Cephalosporins
First generation
    •    CEPHALEXIN                •    CEFAZOLIN

Second generation
    •    CEFOXITIN                  •    CEFACLOR                    •    CEFPROZIL

Third generation
    •    CEFTRIAXONE              •    CEFTAZIDIME                •    CEFOTAXIME

Vancomycin

Inhibitors of Protein Synthesis

Aminoglycosides

    •    STREPTOMYCIN 
•    GENTAMICIN               •    AMIKACIN
•    TOBRAMYCIN              •    NETILMICIN

STREPTOGRAMINS
•    Quinupristin
•    Dalfopristin (Synercid)

OXAZOLIDINONES  
•        LINEZOLID

MACROLIDES
     •    Erythromycin              •    Clarithromycin            •    Azithromycin

CHLORAMPHENICOL  

ERYTHROMYCIN  

CLINDAMYCIN 

Tetracyclines
     •    TETRACYCLINE                •    DOXYCYCLINE           • MINOCYCLINE

Inhibitors of DNA synthesis

Fluoroquinolones
     •    Norfloxacin                     •    Ciprofloxacin              •    Levofloxacin

Sulfonamides
Best urine solubility         
     •    SULFASOXAZOLE               •    SODIUM SULFACETAMIDE (ophthalmic use)
     •    SULFAMETHOXAZOLE 

Topical (burns)
    •   SILVER SULFADIAZINE

TRIMETHOPRIM
    •   Use as TRIMETHOPRIM - SULFAMETHOXZAOLE combo.

Urinary Tract Antiseptics

     •    NITROFURANTOIN

Cationic Surfactants

     •    POLYMIXIN B

Drugs for Anerobic Bacteria Only

     •    Metronidazole

Antimycobacterial Drugs

     •    ISONIAZID                        •    RIFAMPIN                •    DAPSONE
 •    ETHAMBUTOL                    •    STREPTOMYCIN
 •   Clofazamine                       •    Rifabutin

Antifungal Drugs

Polyenes
     •    AMPHOTERICIN B               •    NYSTATIN

Flucytosine
Imidazoles
     •    KETOCONAZOLE                 •    FLUCONAZOLE         •    Voriconazole
     •    MICONAZOLE                     •    ITRACONAZOLE       •     Griseofulvin
     •    Terbinafine

 Antiviral Drugs    

•    AMANTIDINE and        Rimantadine	•    FOSCARNET	•    Lamivudine
•    ACYCLOVIR	•    Didanosine	•    Zanamivir
•    ZIDOVUDINE	•    Valacyclovir	•    Ribavirin
•    GANCICLOVIR	•    Efavirenz	•    Lopinavir
•    Nevirapine	•    Indinavir	•    Nelfinavir
•    Interferon alpha	•    Enfuvirtide	•    Stavudine

Antiparasitic Drugs

Antimalarial
     •    CHLOROQUINE                 •    PYRIMETHAMINE-SULFASOXINE (Fansidar) 
     •    MEFLOQUINE                    •    atovaquone
     •   Quinine
     •    PRIMAQUINE

Antiprotozoal Drugs
Amebiasis and Trichomonas

     •    METRONIDAZOLE              •  Diloxanide             • Iodoquinol

Pneumocystis
     •    TRIMETHOPRIM - SUFAMETHOXAZOLE                •    pentamidine                          
     •    Clindamycin plus primaquine

Toxoplasmosis
     •    PYRIMETHAMINE plus sulfadiazine
     •    Pyrimethamine plus clindamycin

Trichomonas
     •   METRONIDAZOLE

Antihelminthic Drugs

Flatworms
     •    PRAZIQUANTEL

Fluke and Tapeworm Infections
Schistosomiasis
     •    PRAZIQUANTEL

Filariasis
     •    diethylcarbamazine
     •    ivermectin

Intestinal Roundworms (Ascaris), Enterobius (Pinworm) and Hookworm
      •    mebendazole                 •   pyrantel pamoate
      •    Albendazole

Angiostroglyliasis
     •    mebendazole

Trichurius (Whipworm)
Hookworm
     •    mebendazole                    •    albendazole

Trypanosomiasis
     •    nifurtimox or suramin         •    pentamidine

Giadiasis
     •    metronidazole

 Anticancer Drugs and Immunosuppressives

 [Alkyating Agents] - [Antimetabolites] - [Natural Products] - [Antimitotics] -  
 [Miscellaneous] - [Hormones] - [Immunosuppressives]

Alkyating Agents
     •    MECHLORETHAMINE           •    Nitrosoureas                    •    melphalan
     •    CYCLOPHOSPHAMIDE               (carmustine, lomustine)
     •    busulfan                           •    procarbazine

Antimetabolites
 

•    METHOTREXATE	•   6-THIOGUANINE	•   5-Fluorouracil
•   6-MERCAPTOPURINE	•   Cytosine arabinoside	•    gemcitabine
•  Fludarabine
•  Capecitabine

  
Natural Products
 

•    dactinomycin	•    BLEOMYCIN	•    Camptothecin and
•    DAUNORUBICIN	•    mitomycin C	analogs:  irinotecan
•    DOXORUBICIN	•    ETOPOSIDE (VP-16)	topotecan

Antimitotics
     •    VINCRISTINE                     •    VINBLASTINE                    •    paclitaxel/docetaxel

Miscellaneous

 Hormones

•    Estrogens	•    PREDNISONE	•    goserelin
•   Anti-estrogen	•    flutamide
(TAMOXIFEN)	•    leuprolide

Immunosuppressives